A revolution of its kind, the European Public Prosecutor Office, or EPPO, is the first ever supranational financial prosecutorial organization, with jurisdiction to prosecute individuals and companies accused of offences against the financial interest of the European Union. Independent, the EPPO does not report to a national ministry of Justice. With delegated prosecutors in 24 participating EU countries out of 27 Member States, it may conduct investigations relating to offences committed, in whole or in part, in one or several member countries and in the latter case prosecute people in the country of its ultimate choice. By 31 December 2024, the EPPO had 2 666 active investigations, for an estimated damage of over €24.8 billion. Judges granted EPPO’s Prosecutors freezing orders worth €2.42 billion, while the value of assets frozen amounted to €849 million in 2024. Most of the crime reports received by the EPPO come from private parties. Civil plaintiffs may appear in their proceedings. Therefore, companies and individuals worldwide that would engage in unlawful activities when dealing with the European Union need to understand that this is an authority to count with. With experts from Europe and beyond, the panel will address the leading role taken by the EPPO, its challenges and future and its ever-growing interactions with the rest